Phylogeography of Lassa Virus in Nigeria

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Lassa Fever, Nigeria, 2005–2008

To the Editor: Lassa fever affects ≈100,000 persons per year in West Af-rica (1). The disease is caused by Las-sa virus, an arenavirus, and is associated with bleeding and organ failure. The case-fatality rate in hospitalized patients is 10%–20%. The reservoir of the virus is multimammate mice (Mastomys natalensis). Investigations in the 1970s and 1980s pointed to the existence of 3 disease-end...

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BACKGROUND & OBJECTIVES Lassa fever has been endemic in Nigeria since 1969. The rodent Mastomys natalensis has been widely claimed to be the reservoir host of the Lassa virus. This study was designed to investigate the dis- tribution of species of rodents in three states (Edo, Delta and Bayelsa) of Nigeria and to determine the prevalence of Lassa virus amongst trapped rodents in the selected st...

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ژورنال

عنوان ژورنال: Journal of Virology

سال: 2019

ISSN: 0022-538X,1098-5514

DOI: 10.1128/jvi.00929-19